In industries such as pharmaceuticals, biotechnology, food, and cosmetics that have extremely high requirements for hygiene and cleanliness, cleaning and disinfection are not just routine operations, but also an important part of product quality, safety, and regulatory compliance. Mobile high-pressure GMP cleaning machines are a type of professional cleaning equipment designed to meet these needs. They have many advantages, such as strong flexibility, high cleaning power, and compliance with GMP standards.
1. What is a mobile high-pressure GMP cleaning machine?
Mobile high-pressure GMP cleaning machine is a cleaning equipment that integrates high-pressure water pumps, filtration systems, spray guns/nozzles, mobile frames, and control systems. It is designed to meet the cleaning requirements of GMP clean production environments. It can quickly and thoroughly clean surfaces such as production equipment, pipes, containers, floors, and walls through strong high-pressure water flow, and can be flexibly moved to any area that needs to be cleaned.
Unlike traditional high-pressure cleaning equipment, GMP-type equipment uses stainless steel structure, food-grade pipes, no dead angle design, and traceable cleaning records to ensure that the requirements of GMP (Good Manufacturing Practice) standards are fully met.
2. Working Principle
The core working logic of the equipment is as follows:
Pressure system: pressurize clean water or cleaning liquid to 50-150 bar (common range) through a high-pressure pump to form a high-energy kinetic water flow.
Spray system: spray out through a spray gun or nozzle, hit the cleaned surface, and remove dirt, residual dust, and microorganisms.
Filtration system: multi-stage filtration ensures clean water and prevents secondary pollution.
Automatic or semi-automatic control: configured with an operation panel or PLC system, supporting time setting, pressure adjustment, data recording and other functions.
Mobile base and casters: can easily push the equipment into different clean areas to meet multi-area operations.
3. Core technical features
1. GMP design standard
The whole machine is made of stainless steel 304/316L, which is corrosion-resistant and easy to clean;
No dead angle design, rounded corners to avoid dirt residue;
Surface polishing reaches Ra<0.8μm, no dust accumulation.
2. High-pressure and efficient cleaning
The output pressure is adjustable to adapt to different cleaning objects (inner wall of equipment, tank, ground, etc.);
High-pressure water flow effectively decomposes residues without strong chemicals.
3. Movable structure
The equipment is compact and the casters are equipped with brakes, which is suitable for flexible switching between clean areas A, B, C, and D levels;
Avoid multiple fixed equipment occupying space and improve equipment utilization.
4. Cleaning verification and record
Optional printing module and data storage system to record data such as pressure, time, and water usage for easy verification and review.
5. Human-machine safety guarantee
The high-pressure pipeline is equipped with a pressure relief device and an anti-back suction system;
The control system supports functions such as emergency stop, alarm, and permission setting.
4. How to ensure GMP compliance?
GMP (Good Manufacturing Practice) emphasizes key points such as cleaning, cross-contamination control, verification, and traceability. Mobile high-pressure cleaners achieve compliance in the following ways:
1. Material compliance
Parts in contact with drugs and food use FDA-certified materials;
The overall structure does not absorb microorganisms and meets the requirements of cleaning verification.
2. Reasonable structural design
The pipeline routing is simple, removable and easy to clean;
Seamless welding is used to avoid microbial hiding places.
3. Controllable operation
Fixed parameters (pressure, time, temperature) can be set for each cleaning process;
Prevent operators from making arbitrary changes to ensure cleaning consistency.
4. Documentation and traceability
Equipped with electronic or paper recording systems, cleaning reports can be printed;
Meet the basic requirements of GMP for "verifiable and traceable".
5. Easy to clean and disinfect itself
The equipment body can be sterilized at high temperature or CIP cleaned;
Easy to perform daily maintenance to reduce the risk of contamination.
5. Typical application scenarios
Pharmaceutical workshop: cleaning of reactors, mixing tanks, coating machines, and capsule machines;
Food factory: cleaning of clean room floors, filling machines, and conveyor belts;
Cosmetics factory: cleaning of containers, mixing tanks, and the end of packaging lines;
Medical device factory: high-pressure washing of clean room walls and equipment shells;
Biological laboratories: regular disinfection and cleaning of walls, floors, brackets, etc.
6. Selection Recommendations
When purchasing a mobile high-pressure GMP cleaning machine, you should focus on the following parameters:
Item Recommended selection direction
Pressure range 50-150 bar (depending on the cleaning object)
Material requirements 304/316L stainless steel, EP pipes, FDA seals
Mobility Caster design, flexible turning, suitable for non-slip floors
Control system Supports preset programs, data recording, and authority management
Cleaning records Optional electronic storage or printing functions
Whether cleaning validation is supported Verification interface or record document output module
Maintenance convenience Replaceable nozzles, quick disassembly and cleaning filters, etc.
The mobile high-pressure GMP cleaning machine is not only a powerful cleaning equipment, but also a compliant tool that complies with GMP regulations in the pharmaceutical, food, and biological industries. It provides reliable protection for a clean environment through high-pressure flushing technology, standard structural design, and cleaning process control and recording systems.
In the context of increasingly intelligent production processes and increasingly stringent reviews, choosing a compliant, efficient, and flexible GMP cleaning equipment will be an important step in ensuring product quality and corporate compliance operations.
